Sr. Research Associate - Antibody Development (Hybridoma)

Company: BioLegend, Inc.
Location: San Diego
Posted on: October 31, 2024

Job Description:

Job SummaryThis person would be responsible for developing monoclonal and/or polyclonal antibodies in BioLegend derived from immunized animals by performing antigen preparation, host immunization, bleed analysis, cell fusion, and small-scale antibody purification. Techniques involved in this job include antigen formulation, animal immunization and tissue harvesting, cell culture, cell fusion, and antibody analysis using ELISA, WB, and other related techniques.He or She will need to perform project coordination and lead communications with other functional teams across the BioLegend assigned by the manager. In addition, troubleshooting and inventory work will be expected to support the team.Essential FunctionsReasonable accommodations may be made to enable individuals with disabilities to perform the essential functions.Tissue Culture Function

• Perform cell culture activities including thawing, maintenance, freezing with sterile technique
• Perform hybridoma fusion
• Perform ELISA, WB, and flow cytometry analysis
• Work across the teams to support changing priorities
• Maintain lab supplies
• Enforce lab safety and GLPImmunization Function
  • Perform antigen formulation and rodent immunization
  • Rodent bleeding and serum collectionPurification Function
    • Conduct purification of antibodies
    • Update databases as needed
    • Work across the teams to support changing priorities
    • Maintain lab supplies
    • Enforce lab safety and GLPLeadership Function
      • Technical lead to support Jr. lab members
      • Project coordination assigned by the managerOther projects or responsibilities as may be required.Minimum Qualifications - Education and Experience
        • B.S. with generally more than 8 years of relevant working experience OR
        • M.S. with generally 6 years of relevant working experience in antibody development.
        • 3+ years of rodent handling, injection, and serum collection experience
        • 3+ years of mammalian cell culture and cell line maintenancePreferred Qualifications - Education and Experience
          • Experience with hybridoma culture
          • Basic knowledge of immunology including but not limited to antibody and antigen interaction
          • Antibody purification
          • Prior experience of antibody development, ELISA, and WB
          • Work well in a team environmentWork Environment & Physical DemandsLabWhile performing the duties of this job, the employee regularly works in a laboratory environment with occasional data entry on a computer. Occasional exposure to a warehouse environment.The physical demands described here are representative of those that must be met by an employee to successfully perform the essential functions of this job.While performing the duties of this job, the employee is regularly required to use hands and fingers to handle, feel, or operate objects, tools or controls, and reach with hands and arms. The employee is frequently required to stand, talk and hear.What do we offer?We provide competitive and comprehensive benefits to our employees. Below are some highlights of our benefits:
            • Medical, Dental, and Vision Insurance Options
            • Life and Disability Insurance
            • Paid Time-Off
            • Parental Benefits
            • 401k with Company Match
            • Employee Stock Purchase PlanLearn more about Revvity's benefits by visiting our page.*For benefit-eligible roles only. Part-time and temporary roles may not be eligible for all benefits listed. Please reach out to your recruiter for more information.
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Keywords: BioLegend, Inc., Calexico , Sr. Research Associate - Antibody Development (Hybridoma), Other , San Diego, California